Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008733 | 0.91 | TACR2 (0.83) | TACR2TACR1 | |
| SCHEMBL7971804 | 0.90 | TACR2 (0.65) | TACR2TACR1 | |
| SCHEMBL759334 | 0.87 | TACR2 (0.82) | TACR2TACR1 | |
| SCHEMBL6170809 | 0.87 | TACR2 (0.82) | TACR2TACR1 | |
| SCHEMBL8292511 | 0.85 | TACR2 (0.84) | TACR2TACR1 | |
| SCHEMBL8870096 | 0.84 | TACR2 (0.72) | TACR2TACR1 | |
| Hydrochloric Acid SCHEMBL8871548 | 0.83 | TACR2 (0.81) | TACR2 | |
| SCHEMBL8870973 | 0.83 | TACR2 (1.00) | TACR2TACR1 | |
| Hydrochloric Acid SCHEMBL9079366 | 0.83 | TACR2 (0.98) | TACR2 | |
| Hydrochloric Acid SCHEMBL9319119 | 0.83 | TACR2 (0.98) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297259-B1 | HISTAMINE RECEPTOR ANTAGONISTS AND TACHYKININ RECEPTOR ANTAGONISTS. | AVENTIS PHARMACEUTICALS INC. | 2001-10-02 | — | — | US | disclosed |
| US-5998439-A | RESPIRATORY SYSTEM DISORDERS | Hoescht Marion Roussel, Inc. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0882038-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(PIPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997030990-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(PIPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-08-28 | — | — | WO | disclosed |