Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964701 | 0.91 | TACR2 (0.79) | TACR2TACR1 | |
| SCHEMBL759334 | 0.89 | TACR2 (0.82) | TACR2TACR1 | |
| SCHEMBL6170809 | 0.89 | TACR2 (0.82) | TACR2TACR1 | |
| SCHEMBL8292511 | 0.87 | TACR2 (0.84) | TACR2TACR1 | |
| SCHEMBL8870096 | 0.87 | TACR2 (0.72) | TACR2TACR1 | |
| SCHEMBL8870973 | 0.86 | TACR2 (1.00) | TACR2TACR1 | |
| Hydrochloric Acid SCHEMBL8871548 | 0.86 | TACR2 (0.81) | TACR2 | |
| SCHEMBL8291341 | 0.85 | TACR2 (0.74) | TACR2 | |
| Hydrochloric Acid SCHEMBL9319119 | 0.85 | TACR2 (0.98) | TACR2TACR1 | |
| Hydrochloric Acid SCHEMBL9079366 | 0.85 | TACR2 (0.98) | TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576333-A | ASTHMA TREATMENT | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| US-5559131-A | ANTAGONISTS OF TACHYKININS AT THE NEUROKININ 2 RECEPTOR, ANTIASTHMA | ZENECA LIMITED (GB) | 1996-09-24 | — | — | US | disclosed |
| US-5559132-A | ANTAGONIST OF TACHYKININS AT THE NEUROKININ 2 RECEPTOR, ANTIASTHMA | ZENECA LIMITED (GB) | 1996-09-24 | — | — | US | disclosed |
| WO-1994010146-A1 | 4-CARBOXOAMIDO PIPERIDINE DERIVATIVES, INTERMEDIATES AND USE AS NEUROKININ ANTAGONISTS | ZENECA LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |