SCHEMBL7964834

SCHEMBL7964834

Cc1noc(C(=O)NS(=O)(=O)c2ccsc2C(=O)O)c1Br

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 20/20 0.69
EDNRB P24530 9/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4663316 0.81 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7371066 0.76 EDNRA (0.64) EDNRAEDNRB
SCHEMBL3634612 0.74 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7717213 0.73 EDNRA (0.67) EDNRAEDNRB
SCHEMBL8676438 0.72 EDNRB (0.61) EDNRAEDNRB
SCHEMBL7080378 0.72 EDNRA (0.78) EDNRAEDNRB
SCHEMBL2842500 0.72 EDNRA (1.00) EDNRAEDNRB
SCHEMBL8977941 0.72 EDNRB (0.65) EDNRAEDNRB
SCHEMBL4631365 0.71 EDNRA (1.00) EDNRAEDNRB
SCHEMBL4632397 0.71 EDNRA (1.00) EDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248767-B1 VASOCONSTRICTION TEXAS BIOTECHNOLOGY CORP. 2001-06-19 US disclosed