Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.77 |
| ▸ | LAP3 | P28838 | 5/20 | 0.59 |
| ▸ | ANPEP | P15144 | 5/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.57 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578878 | 1.00 | LTA4H (0.77) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL2106383 | 1.00 | LTA4H (0.77) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL8174333 | 1.00 | LTA4H (0.77) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL6339522 | 1.00 | LTA4H (0.77) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL2606756 | 1.00 | LTA4H (0.77) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL2106650 | 1.00 | LTA4H (0.77) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL7964846 | 1.00 | LTA4H (0.77) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL21526210 | 0.98 | LTA4H (0.75) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL21526211 | 0.98 | LTA4H (0.75) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL10628401 | 0.98 | LTA4H (0.75) | LTA4HLAP3ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |