Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308058 | 0.84 | KMT2A (0.59) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL11227804 | 0.82 | KMT2A (0.58) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL11860241 | 0.82 | CYP3A4 (0.44) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL6026762 | 0.80 | NR1H2 (0.59) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL10463880 | 0.80 | SMN1; SMN2 (0.65) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL7607429 | 0.79 | FFAR1 (0.53) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL7965056 | 0.79 | CYP3A4 (0.51) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL6026933 | 0.79 | ELANE (0.68) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL10519529 | 0.79 | MEN1 (0.63) | MEN1KMT2AELANEL3MBTL1POLB | |
| SCHEMBL12117372 | 0.78 | KMT2A (0.54) | MEN1KMT2AELANEL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067523-B2 | Use of pyrone carboxylates for controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20050159479-A1 | Use of pyrone carboxylates for controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-21 | — | — | US | disclosed |
| WO-2003099008-A1 | USE OF PYRONE CARBOXYLATES FOR CONTROLLING PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |
| CN-1118463-C | Simple synthesis of 6-methyl-4-hydroxy-2-pyrone | UNIV CHINA AGRICULTURAL (CN) | 2003-08-20 | — | — | CN | disclosed |
| CN-1288891-A | Simple synthesis of 6-methyl-4-hydroxy-2-pyrone | CHIAN AGRICULTURAL UNIV (CN) | 2001-03-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159479-A1 | Use of pyrone carboxylates for controlling pests | TET1, TET3, CNPY3 | MEN1 1132/4885KMT2A 2113/4885ELANE 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.