Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 10/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685304 | 0.83 | TSHR (0.45) | TLR8TP53SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL7975692 | 0.82 | TLR8 (0.49) | TLR8SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL15780481 | 0.82 | TSHR (0.39) | TP53SMN1; SMN2RAB9AL3MBTL1NPC1 | |
| SCHEMBL14685303 | 0.81 | RAB9A (0.57) | TLR8TP53SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL12362614 | 0.81 | DPP4 (0.44) | TP53SMN1; SMN2RAB9AL3MBTL1NPC1 | |
| SCHEMBL14685206 | 0.80 | TP53 (0.43) | TP53SMN1; SMN2RAB9AL3MBTL1NPC1 | |
| SCHEMBL14685305 | 0.79 | TP53 (0.39) | TP53SMN1; SMN2RAB9AL3MBTL1NPC1 | |
| SCHEMBL14685299 | 0.78 | RAB9A (0.50) | TP53SMN1; SMN2RAB9AL3MBTL1NPC1 | |
| SCHEMBL14685306 | 0.77 | SMN1; SMN2 (0.38) | TP53SMN1; SMN2RAB9AL3MBTL1NPC1 | |
| SCHEMBL15782104 | 0.77 | RAB9A (0.49) | TLR8TP53SMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194396-B1 | ANTIALLERGENS; ANTIINFLAMMATION AGENTS; AUTOIMMUNE DISEASE; ANTISHOCK AGENTS; ANALGESICS; E.G., A 4 OR 7-PHENYLALKYLENE-OXYBENZIMIDAZOLE UNSUBSTITUTED OR SUBSTITUTED IN THE 1,2,3-POSITION WITH AN OXY, AMINO AND/OR THIO GROUP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| US-6083961-A | FOR PREVENTION AND/OR TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES SUCH AS ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE, SHOCK, PAIN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0774462-A1 | HETEROCYCLIC COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |