Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.77 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.77 |
| ▸ | PPARD | Q03181 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BCKDK | O14874 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520041 | 0.87 | KEAP1 (1.00) | KEAP1NFE2L2SLC22A12CYP2A6MAPT | |
| Hydrochloric Acid SCHEMBL6821885 | 0.86 | KEAP1 (0.97) | KEAP1NFE2L2SLC22A12CYP2A6MAPT | |
| SCHEMBL10989414 | 0.83 | KEAP1 (0.55) | KEAP1NFE2L2PPARDPPARASLC22A12 | |
| SCHEMBL15057380 | 0.82 | KEAP1 (0.56) | KEAP1NFE2L2PPARDPPARAPPARG | |
| SCHEMBL15211237 | 0.81 | KEAP1 (0.56) | KEAP1NFE2L2PPARDPPARAPPARG | |
| SCHEMBL15211281 | 0.81 | PPARD (0.63) | KEAP1NFE2L2PPARDPPARAPPARG | |
| SCHEMBL14564404 | 0.81 | KEAP1 (0.55) | KEAP1NFE2L2PPARDPPARAPPARG | |
| SCHEMBL15211203 | 0.80 | KEAP1 (0.55) | KEAP1NFE2L2PPARDPPARAPPARG | |
| SCHEMBL6002566 | 0.80 | CYP2A6 (0.50) | KEAP1NFE2L2SLC22A12CYP2A6MAPT | |
| SCHEMBL2094712 | 0.80 | CYP2A6 (0.58) | KEAP1NFE2L2CYP2A6MAPTBCKDK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |