SCHEMBL7965616

SCHEMBL7965616

O=S(=O)(NCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CCR1 P32246 1/20 0.42
POLB P06746 1/20 0.41
CTDSP1 Q9GZU7 2/20 0.41
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP14 P50281 2/20 0.39
ADAM17 P78536 2/20 0.39
MMP1 P03956 1/20 0.39
HRAS P01112 1/20 0.39
KRAS P01116 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PDK1 Q15118 1/20 0.38
PDK2 Q15119 1/20 0.38
PDK3 Q15120 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8627241 0.84 HTT (0.40) ALDH1A1L3MBTL1POLBMEN1KMT2A
SCHEMBL8628024 0.83 SCN9A (0.41) ALDH1A1L3MBTL1POLBMEN1KMT2A
SCHEMBL8077325 0.83 KMT2A (0.54) ALDH1A1MEN1KMT2AHTT
SCHEMBL8065618 0.82 TRPV1 (0.52)
SCHEMBL8406151 0.82 FFAR4 (0.44) HTTFFAR4
SCHEMBL8519621 0.82 FFAR4 (0.44) HTTFFAR4
SCHEMBL8065652 0.81 TRPV1 (0.51) MMP2MMP9
SCHEMBL8656316 0.81 HTT (0.39) ALDH1A1L3MBTL1POLBMEN1KMT2A
SCHEMBL7977645 0.80 EPHX2 (0.48) ALDH1A1LMNAHPGDPOLBMEN1
SCHEMBL8661564 0.80 RORC (0.39) HTTFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
EP-0824514-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-02-25 EP disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed