Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 12/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 8/20 | 0.57 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.46 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | BAD | Q92934 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.41 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.41 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968444 | 0.94 | PLA2G2A (0.53) | PLA2G2APLA2G1BPLA2G10PLA2G5MEN1 | |
| SCHEMBL817656 | 0.90 | PLA2G2A (0.67) | PLA2G2APLA2G1BPLA2G10PLA2G5MEN1 | |
| SCHEMBL7964676 | 0.89 | PLA2G2A (0.60) | PLA2G2APLA2G1BPLA2G10PLA2G5MEN1 | |
| SCHEMBL7963709 | 0.89 | PLA2G2A (0.58) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7955259 | 0.88 | PLA2G2A (0.57) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7965983 | 0.88 | PLA2G2A (0.47) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7965115 | 0.88 | PLA2G2A (0.58) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7970732 | 0.88 | PLA2G2A (0.47) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7966192 | 0.88 | PLA2G2A (0.56) | PLA2G2APLA2G1BPLA2G10PLA2G5MEN1 | |
| SCHEMBL7969674 | 0.87 | PLA2G2A (0.56) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177440-B1 | THERAPY FOR SEPSIS SHOCK; PHOSPHOLIPASE INHBITOR | ELI LILLY AND COMPANY | 2001-01-23 | — | — | US | disclosed |