Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 4/20 | 0.61 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426070 | 0.86 | CDK5 (0.62) | CDK5CDK5R1TUBB4ATUBBTUBA3C | |
| SCHEMBL13341123 | 0.86 | CDK5 (0.62) | CDK5CDK5R1TUBB4ATUBBTUBA3C | |
| SCHEMBL3426073 | 0.86 | CDK5 (0.62) | CDK5CDK5R1TUBB4ATUBBTUBA3C | |
| SCHEMBL3429396 | 0.83 | CDK5 (0.71) | CDK5CDK5R1TUBB4ATUBBTUBA3C | |
| SCHEMBL3429392 | 0.83 | CDK5 (0.71) | CDK5CDK5R1TUBB4ATUBBTUBA3C | |
| SCHEMBL13341111 | 0.83 | CDK5 (0.71) | CDK5CDK5R1TUBB4ATUBBTUBA3C | |
| SCHEMBL3424811 | 0.80 | CDK5 (0.67) | CDK5CDK5R1BUB1ALDH1A1GFER | |
| SCHEMBL3424813 | 0.80 | CDK5 (0.67) | CDK5CDK5R1BUB1ALDH1A1GFER | |
| SCHEMBL13341120 | 0.80 | CDK5 (0.67) | CDK5CDK5R1BUB1ALDH1A1GFER | |
| SCHEMBL7977986 | 0.77 | TUBB4A (0.60) | CDK5CDK5R1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064680-A1 | MYT1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-07 | — | — | WO | claimed |
| WO-2001064680-A1 | MYT1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-07 | — | — | WO | disclosed |