Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.50 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177767 | 0.97 | CCKBR (0.53) | CCKBRNPY1RRAB9A | |
| SCHEMBL6179720 | 0.88 | CCKBR (0.58) | CCKBRNPY1R | |
| SCHEMBL6179236 | 0.84 | CCKBR (0.54) | CCKBRNPY1RRAB9A | |
| SCHEMBL6177837 | 0.84 | CCKBR (0.54) | CCKBRNPY1RRAB9A | |
| SCHEMBL6178565 | 0.83 | CCKBR (0.49) | CCKBRNPY1R | |
| SCHEMBL6177809 | 0.83 | CCKBR (0.49) | CCKBRNPY1R | |
| SCHEMBL6180505 | 0.83 | CCKBR (0.49) | CCKBRNPY1R | |
| SCHEMBL6176956 | 0.83 | CCKBR (0.49) | CCKBRNPY1R | |
| SCHEMBL6176485 | 0.82 | CCKBR (0.49) | CCKBRNPY1R | |
| SCHEMBL6177275 | 0.82 | CCKBR (0.50) | CCKBRNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |