Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 2/20 | 0.48 |
| ▸ | RHOA | P61586 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | BLK | P51451 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982122 | 0.97 | RHOC (0.45) | RHOCRHOAMRGPRX4CA1CA2 | |
| SCHEMBL7977739 | 0.94 | RHOC (0.51) | RHOCRHOAMRGPRX4CA1CA2 | |
| SCHEMBL8060846 | 0.91 | RHOC (0.47) | RHOCRHOAMRGPRX4CA1CA2 | |
| SCHEMBL7979275 | 0.91 | RHOC (0.45) | RHOCRHOAKMT2ARAB9AMAPT | |
| SCHEMBL7979391 | 0.90 | RHOC (0.47) | RHOCRHOAMRGPRX4CA1CA2 | |
| SCHEMBL7976090 | 0.89 | SCN9A (0.44) | RHOCRHOAPPARD | |
| SCHEMBL7965704 | 0.89 | RHOC (0.42) | RHOCRHOAKMT2ARAB9AMAPT | |
| SCHEMBL8345273 | 0.87 | RHOC (0.50) | RHOCRHOAMRGPRX4CA1CA2 | |
| SCHEMBL8766542 | 0.87 | RHOC (0.50) | RHOCRHOAMRGPRX4CA1CA2 | |
| SCHEMBL7976125 | 0.87 | RHOC (0.44) | RHOCRHOAMRGPRX4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-6028100-A | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-22 | — | — | US | disclosed |
| US-5952386-A | EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-14 | — | — | US | disclosed |