Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979437 | 0.81 | HTR2A (0.47) | HTR2ARETHRH1IDO1 | |
| SCHEMBL8712643 | 0.76 | RET (0.44) | HTR2ARETIDO1 | |
| SCHEMBL8715328 | 0.76 | RET (0.44) | HTR2ARETIDO1 | |
| SCHEMBL5748202 | 0.74 | HTR2A (0.45) | HTR2ARETHRH1KCNA3 | |
| SCHEMBL30729415 | 0.72 | RET (0.66) | HTR2ARETHRH1 | |
| SCHEMBL9244789 | 0.72 | IDO1 (0.59) | HTR2ARETHRH1IDO1 | |
| SCHEMBL13447594 | 0.72 | HTR2A (0.47) | HTR2ARETHRH1IDO1 | |
| SCHEMBL10571581 | 0.71 | PRCP (0.44) | HTR2ARETHRH1 | |
| SCHEMBL11877356 | 0.70 | HTR2A (0.79) | HTR2ARETHRH1 | |
| SCHEMBL12228561 | 0.70 | HTR2A (0.45) | HTR2ARETHRH1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |