Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 18/20 | 0.63 |
| ▸ | HRH1 | P35367 | 18/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979796 | 1.00 | HRH2 (0.63) | HRH2HRH1THRBOPRK1 | |
| SCHEMBL7242978 | 0.77 | HRH2 (1.00) | HRH2HRH1 | |
| SCHEMBL7252046 | 0.77 | HRH2 (1.00) | HRH2HRH1 | |
| SCHEMBL7978201 | 0.73 | HRH2 (0.58) | HRH2HRH1OPRK1 | |
| SCHEMBL7982282 | 0.73 | HRH2 (0.68) | HRH2HRH1 | |
| SCHEMBL7979703 | 0.73 | HRH2 (0.66) | HRH2HRH1 | |
| SCHEMBL7976390 | 0.72 | HRH1 (0.67) | HRH2HRH1 | |
| SCHEMBL7976458 | 0.71 | HRH2 (0.67) | HRH2HRH1 | |
| Acetic Acid SCHEMBL2824054 | 0.71 | HRH3 (0.66) | — | |
| SCHEMBL7246380 | 0.70 | HRH2 (1.00) | HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | disclosed |