Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 16/20 | 0.58 |
| ▸ | HRH1 | P35367 | 16/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980024 | 0.85 | HRH2 (0.51) | HRH2HRH1 | |
| SCHEMBL7978323 | 0.82 | HRH2 (0.54) | HRH2HRH1 | |
| SCHEMBL7982448 | 0.80 | HRH2 (0.52) | HRH2HRH1 | |
| SCHEMBL7979796 | 0.73 | HRH2 (0.63) | HRH2HRH1OPRK1 | |
| SCHEMBL7242978 | 0.73 | HRH2 (1.00) | HRH2HRH1 | |
| SCHEMBL7252046 | 0.73 | HRH2 (1.00) | HRH2HRH1 | |
| SCHEMBL7966014 | 0.73 | HRH2 (0.63) | HRH2HRH1OPRK1 | |
| SCHEMBL4213022 | 0.71 | AKT1 (0.54) | HRH2HRH1AKT1 | |
| SCHEMBL10180336 | 0.71 | AKT1 (0.54) | HRH2HRH1AKT1 | |
| SCHEMBL4213020 | 0.71 | AKT1 (0.54) | HRH2HRH1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |