Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flunamine SCHEMBL2110008 | 0.89 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| Flunamine SCHEMBL7434697 | 0.87 | SLC6A2 (0.56) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| Halonamine SCHEMBL2110923 | 0.81 | SLC6A2 (0.56) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| SCHEMBL14163724 | 0.80 | SLC6A2 (0.53) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| SCHEMBL7437880 | 0.73 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| SCHEMBL4283044 | 0.73 | SLC6A2 (0.58) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| SCHEMBL4278117 | 0.73 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| SCHEMBL423398 | 0.73 | SLC6A2 (0.62) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| SCHEMBL10580002 | 0.71 | LMNA (0.60) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 | |
| SCHEMBL8746929 | 0.70 | SLC6A2 (0.54) | SLC6A4SLC6A3SLC6A2SIGMAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |