Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 15/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7962708 | 0.99 | PTGES (0.37) | PTGES | |
| SCHEMBL7964677 | 0.95 | HDAC3 (0.34) | PTGES | |
| SCHEMBL7966817 | 0.94 | HDAC3 (0.33) | PTGES | |
| Hydrochloric Acid SCHEMBL7963051 | 0.94 | HDAC3 (0.34) | PTGES | |
| SCHEMBL7967808 | 0.94 | HDAC3 (0.32) | PTGES | |
| SCHEMBL7964608 | 0.94 | ALK (0.34) | — | |
| Hydrochloric Acid SCHEMBL7975686 | 0.94 | HDAC3 (0.32) | PTGES | |
| Hydrochloric Acid SCHEMBL7472559 | 0.93 | ALK (0.34) | — | |
| SCHEMBL7480416 | 0.93 | ABCB1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7968186 | 0.93 | HDAC3 (0.32) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |