Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954944 | 0.83 | HTR2C (0.46) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL7971870 | 0.82 | HTR2C (0.47) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL7763589 | 0.82 | HTR2C (0.47) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL7468424 | 0.82 | HTR2C (0.47) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL7965605 | 0.81 | HTR2C (0.46) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL7955395 | 0.81 | HTR2C (0.46) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL25901442 | 0.78 | HTR2C (0.53) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL7970669 | 0.77 | HTR2C (0.43) | HTR2CSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7964140 | 0.77 | ADORA2B (0.47) | HTR2CSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7966304 | 0.77 | HTR2C (0.43) | HTR2CSMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268381-B1 | Taxane derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-1044971-A1 | TAXANE DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-10-18 | — | — | EP | disclosed |