Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 14/20 | 0.75 |
| ▸ | PTGER3 | P43115 | 14/20 | 0.75 |
| ▸ | PTGER2 | P43116 | 14/20 | 0.75 |
| ▸ | PTGER1 | P34995 | 11/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804201 | 0.86 | PTGER2 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7804198 | 0.86 | PTGER2 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7966426 | 0.82 | PTGER4 (0.82) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7966425 | 0.82 | PTGER4 (0.82) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7947804 | 0.82 | PTGER4 (0.82) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7957266 | 0.78 | PTGER4 (0.70) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7959167 | 0.75 | PTGER2 (0.80) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7959170 | 0.75 | PTGER2 (0.80) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7955463 | 0.71 | PTGER2 (0.71) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7955466 | 0.71 | PTGER2 (0.71) | PTGER4PTGER3PTGER2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |