Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 17/20 | 0.82 |
| ▸ | PTGER3 | P43115 | 17/20 | 0.82 |
| ▸ | PTGER2 | P43116 | 17/20 | 0.82 |
| ▸ | PTGER1 | P34995 | 11/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966425 | 1.00 | PTGER4 (0.82) | PTGER4PTGER3PTGER2PTGER1L3MBTL1 | |
| SCHEMBL7804201 | 0.90 | PTGER2 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7804198 | 0.90 | PTGER2 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7947804 | 0.88 | PTGER4 (0.82) | PTGER4PTGER3PTGER2PTGER1L3MBTL1 | |
| SCHEMBL7966428 | 0.82 | PTGER4 (0.75) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7959170 | 0.79 | PTGER2 (0.80) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7959167 | 0.79 | PTGER2 (0.80) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7957258 | 0.79 | PTGER4 (0.76) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7957261 | 0.79 | PTGER4 (0.76) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7955466 | 0.73 | PTGER2 (0.71) | PTGER4PTGER3PTGER2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |