Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 10/20 | 0.56 |
| ▸ | GABRD | O14764 | 10/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.56 |
| ▸ | GABRE | P78334 | 10/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972588 | 0.79 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7957547 | 0.79 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7970651 | 0.78 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7967550 | 0.77 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7970220 | 0.77 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7970275 | 0.75 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7972910 | 0.75 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7969715 | 0.73 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7966892 | 0.72 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6926965 | 0.72 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007413-A1 | 1-ARYL-3-THIOALKYL PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS INSECTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |