Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973450 | 1.00 | KDM4E (0.61) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL7966546 | 1.00 | KDM4E (0.61) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL7973457 | 1.00 | KDM4E (0.61) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL7967539 | 0.95 | KDM4E (0.68) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL7966534 | 0.95 | KDM4E (0.68) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL7966530 | 0.95 | KDM4E (0.68) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL7967532 | 0.95 | KDM4E (0.68) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL7966711 | 0.90 | KDM4E (0.74) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL7966717 | 0.90 | KDM4E (0.74) | KDM4EACHEALDH1A1HPGDALOX15 | |
| SCHEMBL8085980 | 0.89 | KDM4E (0.76) | KDM4EACHEALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |