Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.45 |
| ▸ | PTGIR | P43119 | 15/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960023 | 0.78 | PTGIR (0.67) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL8053215 | 0.78 | PTGIR (0.48) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL7966687 | 0.77 | TBXA2R (0.45) | TBXA2RPTGIRTHRATHRBKDM4E | |
| SCHEMBL7956157 | 0.74 | TBXA2R (0.58) | TBXA2RPTGIRTHRATHRBKDM4E | |
| SCHEMBL7948850 | 0.73 | TBXA2R (0.46) | TBXA2RPTGIRTHRATHRBKDM4E | |
| SCHEMBL7948857 | 0.73 | TBXA2R (0.50) | TBXA2RPTGIRTHRATHRBKDM4E | |
| SCHEMBL7958516 | 0.73 | PTGIR (0.56) | TBXA2RPTGIRTHRATHRBKDM4E | |
| SCHEMBL7959498 | 0.73 | PTGIR (0.76) | TBXA2RPTGIRTHRATHRBKDM4E | |
| SCHEMBL7965748 | 0.71 | PTGIR (0.59) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL7958687 | 0.71 | TBXA2R (0.50) | TBXA2RPTGIRTHRATHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |