Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.57 |
| ▸ | CNR2 | P34972 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376195 | 0.79 | NAAA (0.56) | CNR1CNR2 | |
| SCHEMBL8373891 | 0.79 | NAAA (0.56) | CNR1CNR2 | |
| SCHEMBL8374187 | 0.79 | NAAA (0.56) | CNR1CNR2 | |
| SCHEMBL9461596 | 0.78 | CNR1 (0.62) | CNR1CNR2CYP3A4CYP2D6CYP2C19 | |
| Dimethylamine SCHEMBL9167323 | 0.75 | CNR1 (0.59) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL9461958 | 0.74 | CNR1 (0.57) | CNR1CNR2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28041163 | 0.73 | CNR1 (1.00) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL7595831 | 0.73 | CNR1 (0.59) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL9854656 | 0.70 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL20803506 | 0.70 | CNR1 (0.69) | CNR1CNR2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002364-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2001-01-11 | — | — | WO | disclosed |