Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 18/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 18/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18547931 | 0.82 | CNR1 (0.47) | — | |
| SCHEMBL24330059 | 0.78 | HTR2A (0.47) | HTR2AGSK3B | |
| SCHEMBL14338763 | 0.78 | PDPK1 (0.50) | TLR9TLR8TLR7HTR2A | |
| Hydrochloric Acid SCHEMBL7955360 | 0.77 | HTR2A (0.46) | HTR2AGSK3B | |
| SCHEMBL7966944 | 0.77 | TLR9 (0.36) | TLR9TLR8TLR7HTR2A | |
| SCHEMBL29869220 | 0.74 | HTR2C (0.50) | HTR2A | |
| SCHEMBL1545976 | 0.74 | HTR2C (0.50) | HTR2A | |
| SCHEMBL7966309 | 0.74 | MAPK14 (0.40) | TLR9TLR8TLR7HTR2A | |
| SCHEMBL24148934 | 0.71 | MAP2K4 (0.47) | — | |
| SCHEMBL12120600 | 0.71 | HTR1D (0.41) | HTR2AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303627-B1 | FOR THERAPY OF PHYSIOLOGICAL AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2001-10-16 | — | — | US | disclosed |
| WO-1999065487-A1 | INHIBITORS OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0965587-A1 | Tetrahydropyridinyl- and piperidinyl Inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |