SCHEMBL7967362

SCHEMBL7967362

CC(CNCc1ccc(Cl)nc1)Cc1ccc(C(C)(C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.43
ERAP2 Q6P179 1/20 0.43
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 2/20 0.40
GAA P10253 2/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
OXTR P30559 1/20 0.39
AVPR1A P37288 1/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
BCHE P06276 3/20 0.36
BACE1 P56817 2/20 0.36
EBP Q15125 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
DNM1 Q05193 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6599938 0.81 CHRM5 (0.42) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL7992401 0.78 KDM4E (0.46) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL27977498 0.77 KDM4E (0.51) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL6625079 0.76 TP53 (0.38) TP53TSHRALDH1A1EBPSIGMAR1
SCHEMBL6317403 0.75 KDM4E (0.49) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL7999050 0.75 KDM4E (0.49) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL15926086 0.75 KDM4E (0.49) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL4881633 0.72 TRPV1 (0.53)
SCHEMBL7969008 0.72 TP53 (0.50) ANPEPERAP2TP53TSHRKDM4E
SCHEMBL9279836 0.72 GAA (0.63) KDM4EGAAMAPTL3MBTL1OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271385-B1 FUNGICIDES (SUCH AS THOSE FOR USE IN FARMING AND HORTICULTURE). KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-08-07 US disclosed
EP-1020441-A1 N-HETEROCYCLIC METHYLPROPYLAMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND GERMICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-07-19 EP disclosed