Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27977498 | 0.87 | KDM4E (0.51) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL7992401 | 0.84 | KDM4E (0.46) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL7999050 | 0.84 | KDM4E (0.49) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL15926086 | 0.84 | KDM4E (0.49) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL9279836 | 0.80 | GAA (0.63) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL229169 | 0.80 | GAA (0.51) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL9316397 | 0.80 | GAA (0.51) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL6664519 | 0.80 | KDM4E (0.51) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL16585876 | 0.79 | KDM4E (0.47) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL502303 | 0.79 | GAA (0.50) | KDM4EGAAMAPTL3MBTL1OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1289507-C | Novel insecticidal pyrrole compounds | BAYER AG (DE) | 2006-12-13 | — | — | CN | disclosed |
| US-6887905-B2 | Treatment of depression or generalized anxiety disorder | PFIZER INC (US) | 2005-05-03 | — | — | US | disclosed |
| US-6838462-B2 | Insecticidal azoles | BAYER CROPSCIENCE LP (DE) | 2005-01-04 | — | — | US | disclosed |
| EP-1383773-B1 | NOVEL INSECTICIDAL AZOLES | BAYER CROPSCIENCE AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| US-20040209896-A1 | Novel insecticidal azoles | BAYER CROPSCIENCE AG (DE) | 2004-10-21 | — | — | US | disclosed |
| CN-1514840-A | Novel insecticidal pyrrole compounds | �ݶ�ũ�����ѧ�ɷݹ�˾ | 2004-07-21 | — | — | CN | disclosed |
| US-6297374-B1 | Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-02 | — | — | US | disclosed |
| US-6022967-A | 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-08 | — | — | US | disclosed |
| US-5750704-A | INSECTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0609811-B1 | Process for preparing 2-chloro-5-aminomethyl-pyridines | KOEI CHEMICAL CO (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5424437-A | Process for preparing a 2-chloro-5-aminomethyl-pyridine | KOEI CHEMICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0609811-A1 | Process for preparing 2-chloro-5-aminomethyl-pyridine | KOEI CHEMICAL CO., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5304564-A | Insecticidal guanidine derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5298507-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0547451-A1 | Guanidine derivatives as inseticides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-06-23 | — | — | EP | disclosed |
| US-5204360-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209896-A1 | Novel insecticidal azoles | CYP51A1, CRY1, CYP4X1 | KDM4E 1556/4885GAA 2831/4885MAPT 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.