Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.79 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.57 |
| ▸ | CCKAR | P32238 | 2/20 | 0.57 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.55 |
| ▸ | OXTR | P30559 | 4/20 | 0.53 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.53 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761230 | 0.93 | CCKBR (0.79) | CCKBRKCNH2SCN9ACCKARSENP1 | |
| SCHEMBL9525360 | 0.88 | CCKBR (1.00) | CCKBRKCNH2SCN9ACCKARNOTCH1 | |
| SCHEMBL9525366 | 0.88 | CCKBR (1.00) | CCKBRKCNH2SCN9ACCKARNOTCH1 | |
| SCHEMBL9526276 | 0.88 | CCKBR (1.00) | CCKBRKCNH2SCN9ACCKARNOTCH1 | |
| SCHEMBL9526270 | 0.88 | CCKBR (1.00) | CCKBRKCNH2SCN9ACCKARNOTCH1 | |
| SCHEMBL8746541 | 0.88 | CCKBR (0.75) | CCKBRKCNH2SCN9ACCKARSENP1 | |
| SCHEMBL10435092 | 0.88 | CCKBR (0.75) | CCKBRKCNH2SCN9ACCKARSENP1 | |
| SCHEMBL8746530 | 0.88 | CCKBR (0.75) | CCKBRKCNH2SCN9ACCKARSENP1 | |
| SCHEMBL8420210 | 0.88 | KCNH2 (0.72) | CCKBRKCNH2SCN9ACCKARSENP1 | |
| SCHEMBL8422703 | 0.88 | KCNH2 (0.72) | CCKBRKCNH2SCN9ACCKARSENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214823-B1 | CARDIOVASCULAR DISORDERS | MERCK & CO., INC. | 2001-04-10 | — | — | US | disclosed |