Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28851736 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1HPGDPARP1ACHE | |
| SCHEMBL50426 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1HPGDPARP1ACHE | |
| SCHEMBL11978323 | 0.69 | KDM4E (0.41) | KDM4EALDH1A1HPGDPARP1ACHE | |
| SCHEMBL13708660 | 0.68 | PARP1 (0.49) | KDM4EALDH1A1HPGDPARP1ACHE | |
| SCHEMBL2464529 | 0.67 | ADRA1A (0.49) | KDM4EALDH1A1HPGDPARP1ACHE | |
| SCHEMBL2466147 | 0.67 | ADRA1A (0.49) | KDM4EALDH1A1HPGDPARP1ACHE | |
| SCHEMBL354017 | 0.67 | ADRA1A (0.49) | KDM4EALDH1A1HPGDPARP1ACHE | |
| SCHEMBL13616708 | 0.67 | POLL (0.49) | KDM4EALDH1A1HPGDPARP1ACHE | |
| SCHEMBL8501452 | 0.67 | CYP2D6 (0.35) | KDM4EALDH1A1GAACYP3A4LMNA | |
| SCHEMBL354324 | 0.66 | KDM4E (1.00) | KDM4EALDH1A1HPGDPARP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262064-B1 | AN ACTAHYDROBENZO(F)QUINOLINE-BASED COMPOUND | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION | 2001-07-17 | — | — | US | disclosed |
| US-5863928-A | TREATMENT OF PSYCHOTIC DISORDERS, PARKINSON'S DISEASE; SEDATIVES | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATION. (US) | 1999-01-26 | — | — | US | disclosed |