Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 16/20 | 0.81 |
| ▸ | ITGA4 | P13612 | 16/20 | 0.81 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.73 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357321 | 0.89 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7957906 | 0.85 | ITGB1 (0.76) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7957800 | 0.84 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL3901901 | 0.82 | ITGB1 (0.59) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL3901904 | 0.82 | ITGB1 (0.59) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7355597 | 0.80 | ITGB1 (0.74) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7970886 | 0.78 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL29575786 | 0.78 | ITGB1 (0.65) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7957794 | 0.75 | ITGB1 (0.96) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7352118 | 0.75 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271252-B1 | ASTHMA THERAPY, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS,MULTIPLE SCLEROSIS, AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-08-07 | — | — | US | disclosed |