Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967536 | 1.00 | ADRB2 (0.42) | ADRB2ADRB3ADRA1ACHRM3MCHR1 | |
| SCHEMBL7980626 | 0.94 | MAPT (0.42) | ADRB2ADRB3ALOX15 | |
| SCHEMBL7980624 | 0.94 | MAPT (0.42) | ADRB2ADRB3ALOX15 | |
| SCHEMBL7967366 | 0.93 | ADRB3 (0.47) | ADRB2ADRB3ADRA1A | |
| Hydrochloric Acid SCHEMBL7978869 | 0.92 | ADRB3 (0.47) | ADRB2ADRB3ADRA1A | |
| Hydrochloric Acid SCHEMBL7978873 | 0.92 | ADRB3 (0.47) | ADRB2ADRB3ADRA1A | |
| SCHEMBL6911399 | 0.89 | ADRB3 (0.44) | ADRB2ADRB3ADRA1A | |
| SCHEMBL7106651 | 0.89 | ADRB3 (0.44) | ADRB2ADRB3ADRA1A | |
| SCHEMBL7106659 | 0.89 | ADRB3 (0.44) | ADRB2ADRB3ADRA1A | |
| SCHEMBL7983630 | 0.89 | ADRB2 (0.41) | ADRB2ADRB3ADRA1AMCHR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |