Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970083 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL7970087 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL7967764 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL7967760 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL7970139 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL7972734 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL7972728 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL7970145 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL7970147 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2POLBSLC6A2 | |
| SCHEMBL3356877 | 0.90 | THRB (0.49) | KDM4EALDH1A1SMN1; SMN2POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |