Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576846 | 0.83 | SMN1; SMN2 (0.44) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL7247968 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1GAAL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL19972267 | 0.81 | ALOX15 (0.45) | MAPTALDH1A1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7720668 | 0.78 | MAPT (0.64) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL2815023 | 0.78 | MAPT (0.51) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL7139968 | 0.78 | MAPT (0.67) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL1508442 | 0.77 | MAPT (0.66) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL5692340 | 0.77 | MAPT (0.66) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL5692343 | 0.77 | MAPT (0.66) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL7138665 | 0.76 | MAPT (0.64) | MAPTKDM4ELMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002357-A2 | PROCESS FOR THE SYNTHESIS OF 4-(4'-FLUOROPHENYL)-PIPERIDINES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-01-11 | — | — | WO | disclosed |