Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC11A2 | P49281 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 4/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707197 | 0.80 | AHR (0.54) | SLC11A2HTTRAB9AMEN1KMT2A | |
| SCHEMBL6707897 | 0.79 | FLT1 (0.53) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL4631791 | 0.79 | AURKA (0.51) | SLC11A2AURKAKDM4ERAB9AMEN1 | |
| SCHEMBL16019870 | 0.77 | TYK2 (0.51) | AURKAAURKBHTTRAB9AMEN1 | |
| SCHEMBL16019869 | 0.77 | ITGB1 (0.47) | AURKAAURKBKDM4EHTTRAB9A | |
| SCHEMBL16019868 | 0.76 | TYK2 (0.46) | AURKAAURKBKDM4EHTTRAB9A | |
| SCHEMBL16019866 | 0.75 | MEN1 (0.46) | AURKAAURKBKDM4ERAB9AMEN1 | |
| SCHEMBL6707922 | 0.74 | KIF11 (0.48) | AURKAHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28869489 | 0.73 | AURKA (0.47) | SLC11A2AURKAKDM4ERAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL28469900 | 0.72 | AURKA (0.46) | SLC11A2AURKAKDM4ERAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316479-B1 | ANTICANCER AGENTS | SUGEN, INC. | 2001-11-13 | — | — | US | disclosed |