Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971186 | 0.86 | OPRD1 (0.48) | OPRD1 | |
| SCHEMBL7967877 | 0.80 | — | — | |
| SCHEMBL7967433 | 0.80 | OPRD1 (0.51) | OPRD1 | |
| SCHEMBL7973745 | 0.79 | OPRD1 (0.45) | OPRD1 | |
| SCHEMBL7968614 | 0.78 | OPRD1 (0.51) | OPRD1 | |
| SCHEMBL7967521 | 0.78 | OPRD1 (0.59) | OPRD1 | |
| SCHEMBL7971024 | 0.78 | EP300 (0.46) | — | |
| SCHEMBL7971321 | 0.77 | OPRD1 (0.50) | OPRD1 | |
| SCHEMBL7973648 | 0.77 | — | — | |
| SCHEMBL7958113 | 0.77 | OPRD1 (0.49) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |