Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971485 | 0.89 | OPRD1 (0.52) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7967717 | 0.87 | OPRD1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7973891 | 0.83 | OPRD1 (0.58) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7971327 | 0.75 | CYP1A2 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8847666 | 0.75 | MAPT (0.53) | — | |
| SCHEMBL2752684 | 0.74 | OPRD1 (0.66) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6935776 | 0.74 | OPRD1 (0.66) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7968871 | 0.74 | CYP1A2 (0.44) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7973770 | 0.73 | OPRD1 (0.54) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7967710 | 0.73 | OPRD1 (0.55) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |