Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788316 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AHPGDCYP3A4GAA | |
| SCHEMBL2574998 | 0.74 | CYP3A4 (0.46) | MEN1KMT2AHPGDCYP3A4GAA | |
| SCHEMBL1308058 | 0.72 | KMT2A (0.59) | MEN1KMT2AHPGDCYP3A4GAA | |
| SCHEMBL11227804 | 0.71 | KMT2A (0.58) | MEN1KMT2AHPGDCYP3A4GAA | |
| SCHEMBL11843818 | 0.70 | POLB (0.57) | MEN1KMT2AHPGDCYP3A4GAA | |
| SCHEMBL1975589 | 0.69 | KDM4E (0.61) | MEN1KMT2AHPGDGAAKDM4E | |
| SCHEMBL1682172 | 0.69 | CYP3A4 (0.68) | MEN1KMT2AHPGDCYP3A4GAA | |
| SCHEMBL5188741 | 0.68 | KDM4E (0.59) | MEN1KMT2AHPGDGAAKDM4E | |
| SCHEMBL7963459 | 0.68 | ALDH1A1 (0.45) | MEN1KMT2AHPGDCYP3A4GAA | |
| SCHEMBL11861102 | 0.68 | KDM4E (0.59) | MEN1KMT2AHPGDGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |