SCHEMBL796887

SCHEMBL796887

CCOC(=O)CCC1NC(=O)OC1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.37
TDP1 Q9NUW8 3/20 0.36
ABL1 P00519 2/20 0.36
RIN1 Q13671 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 3/20 0.35
USP2 O75604 1/20 0.35
ALOX15 P16050 1/20 0.35
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
LMNA P02545 3/20 0.34
TSHR P16473 3/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14366420 1.00 CYP1A2 (0.37) CYP1A2TDP1ABL1RIN1SMN1; SMN2
SCHEMBL21594597 0.91 CYP1A2 (0.41) CYP1A2TDP1ABL1RIN1SMN1; SMN2
SCHEMBL9886435 0.85 PRKCA (0.40) ALDH1A1GAALMNA
SCHEMBL797438 0.84 CYP1A2 (0.48) CYP1A2TDP1ABL1RIN1SMN1; SMN2
SCHEMBL10038782 0.84 TSHR (0.39) TDP1ALDH1A1GAALMNATSHR
SCHEMBL23219624 0.84 POLB (0.38) TDP1ALDH1A1GAALMNATSHR
SCHEMBL19472861 0.84 POLB (0.32) TDP1SMN1; SMN2TSHRL3MBTL1POLB
SCHEMBL21594594 0.81 GSTP1 (0.40) ALDH1A1TSHRL3MBTL1
SCHEMBL11339470 0.81 GSTP1 (0.40) ALDH1A1TSHRL3MBTL1
SCHEMBL9886383 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2406300-B1 METHOD FOR THE PRODUCTION OF POLYAMINO ACID RANDOM COPOLYMERS SIGMA ALDRICH CO LLC (US) 2016-11-16 EP disclosed
US-20120071612-A1 METHOD FOR THE PRODUCTION OF POLYAMINO ACID RANDOM COPOLYMERS SIGMA-ALDRICH CO., LLC (US) 2012-03-22 US disclosed
US-20120071612-A1 METHOD FOR THE PRODUCTION OF POLYAMINO ACID RANDOM COPOLYMERS SIGMA-ALDRICH CO., LLC (US) 2012-03-22 US disclosed
WO-2010104789-A1 METHOD FOR THE PRODUCTION OF POLYAMINO ACID RANDOM COPOLYMERS SIGMA-ALDRICH CO. (US) 2010-09-16 WO disclosed
US-7317070-B1 Process for the preparation of polyamino acids SIGMA-ALDRICH CO. (US) 2008-01-08 US disclosed