Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955785 | 1.00 | KDM1A (0.46) | KDM1AMAOAMAOBABCB1KDM1B | |
| Hydrochloric Acid SCHEMBL7965168 | 0.99 | KDM1A (0.45) | KDM1AMAOAMAOBABCB1KDM1B | |
| Hydrochloric Acid SCHEMBL7965167 | 0.99 | KDM1A (0.45) | KDM1AMAOAMAOBABCB1KDM1B | |
| SCHEMBL10738870 | 0.89 | KDM1A (0.41) | KDM1AMAOAMAOBABCB1KDM1B | |
| SCHEMBL10736440 | 0.89 | KDM1A (0.41) | KDM1AMAOAMAOBABCB1KDM1B | |
| SCHEMBL8149738 | 0.82 | HTR2C (0.49) | KDM1AMAOAMAOBCYP2D6CYP2C19 | |
| SCHEMBL7955781 | 0.81 | DPP4 (0.43) | ABCB1ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL7968924 | 0.81 | DPP4 (0.43) | ABCB1ALDH1A1KDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL7955138 | 0.79 | KDM1A (0.43) | KDM1AMAOAMAOBCYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL6961572 | 0.79 | KDM1A (0.43) | KDM1AMAOAMAOBCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255315-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | disclosed |