Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955781 | 1.00 | DPP4 (0.43) | DPP4DPP9DPP7DPP8KDM4E | |
| SCHEMBL7968925 | 0.81 | KDM1A (0.46) | DPP4DPP9DPP7DPP8KDM4E | |
| SCHEMBL7955785 | 0.81 | KDM1A (0.46) | DPP4DPP9DPP7DPP8KDM4E | |
| Hydrochloric Acid SCHEMBL7965168 | 0.80 | KDM1A (0.45) | DPP4DPP9DPP7DPP8KDM4E | |
| Hydrochloric Acid SCHEMBL7965167 | 0.80 | KDM1A (0.45) | DPP4DPP9DPP7DPP8KDM4E | |
| SCHEMBL7970182 | 0.78 | DPP4 (0.49) | DPP4DPP9DPP7DPP8KDM4E | |
| SCHEMBL15422012 | 0.76 | CHRM1 (0.49) | DPP4DPP9DPP7DPP8MEN1 | |
| SCHEMBL10736440 | 0.76 | KDM1A (0.41) | DPP4DPP9DPP7DPP8KDM4E | |
| SCHEMBL10738870 | 0.76 | KDM1A (0.41) | DPP4DPP9DPP7DPP8KDM4E | |
| Hydrochloric Acid SCHEMBL2146257 | 0.74 | CHRM1 (0.47) | DPP4DPP9DPP7DPP8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255315-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | disclosed |