Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 19/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 6/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.54 |
| ▸ | PLA2G2E | Q9NZK7 | 3/20 | 0.54 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.54 |
| ▸ | PLA2G2F | Q9BZM2 | 2/20 | 0.52 |
| ▸ | PLA2G2D | Q9UNK4 | 2/20 | 0.52 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.52 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.52 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.52 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.52 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862240 | 0.91 | PLA2G2A (0.63) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL817831 | 0.91 | PLA2G2A (0.63) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7962970 | 0.90 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7954392 | 0.90 | PLA2G2A (0.57) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7967381 | 0.90 | PLA2G2A (0.68) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7967694 | 0.90 | PLA2G2A (0.51) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL7954036 | 0.88 | PLA2G2A (0.46) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL817316 | 0.88 | PLA2G2A (0.53) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL29862777 | 0.88 | PLA2G2A (0.53) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL819829 | 0.88 | PLA2G2A (0.54) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177440-B1 | THERAPY FOR SEPSIS SHOCK; PHOSPHOLIPASE INHBITOR | ELI LILLY AND COMPANY | 2001-01-23 | — | — | US | disclosed |