Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.69 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.56 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7691594 | 0.99 | EGLN1 (0.67) | EGLN1GRM4PSDKDRALDH1A1 | |
| SCHEMBL19347364 | 0.91 | EGLN1 (0.66) | EGLN1PSDALDH1A1NPC1HTT | |
| Hydrochloric Acid SCHEMBL7686856 | 0.89 | EGLN1 (0.70) | EGLN1PSDKDRALDH1A1MAPT | |
| SCHEMBL7685082 | 0.86 | EGLN1 (0.78) | EGLN1KDRALDH1A1NPC1RAB9A | |
| SCHEMBL7953380 | 0.85 | EGLN1 (0.73) | EGLN1GRM4PSDKDRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7691643 | 0.85 | EGLN1 (0.76) | EGLN1KDRALDH1A1NPC1RAB9A | |
| SCHEMBL7965479 | 0.85 | EGLN1 (0.72) | EGLN1PSDKDRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7690422 | 0.84 | EGLN1 (0.71) | EGLN1GRM4PSDKDRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7690327 | 0.84 | EGLN1 (0.70) | EGLN1PSDKDRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7689878 | 0.82 | EGLN1 (0.67) | EGLN1ALDH1A1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310211-B1 | ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 | PHARMACIA & UPJOHN COMPANY | 2001-10-30 | — | — | US | claimed |