Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.73 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7690422 | 0.99 | EGLN1 (0.71) | EGLN1GRM4HDAC6KDRPSD | |
| SCHEMBL7965479 | 0.90 | EGLN1 (0.72) | EGLN1KDRPSDALDH1A1 | |
| Hydrochloric Acid SCHEMBL7690327 | 0.89 | EGLN1 (0.70) | EGLN1KDRPSDALDH1A1 | |
| SCHEMBL7685082 | 0.86 | EGLN1 (0.78) | EGLN1KDRALDH1A1L3MBTL1 | |
| SCHEMBL7964145 | 0.85 | EGLN1 (0.73) | EGLN1KDRALDH1A1MEN1KMT2A | |
| SCHEMBL7687778 | 0.85 | EGLN1 (0.73) | EGLN1KDRALDH1A1MEN1KMT2A | |
| SCHEMBL7969151 | 0.85 | EGLN1 (0.69) | EGLN1GRM4KDRPSDALDH1A1 | |
| SCHEMBL8309229 | 0.85 | EGLN1 (0.73) | EGLN1KDRALDH1A1MEN1KMT2A | |
| SCHEMBL8312850 | 0.85 | EGLN1 (0.73) | EGLN1KDRPSDALDH1A1P2RX1 | |
| SCHEMBL2201326 | 0.84 | EGLN1 (1.00) | EGLN1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310211-B1 | ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 | PHARMACIA & UPJOHN COMPANY | 2001-10-30 | — | — | US | claimed |
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |