Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 4/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968051 | 0.86 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1NFE2L2CYP1A1CYP1A2 | |
| SCHEMBL7958260 | 0.73 | GPBAR1 (0.36) | HSP90AA1HSP90AB1NFE2L2CYP1A2L3MBTL1 | |
| SCHEMBL7958876 | 0.73 | CHRM5 (0.37) | GPBAR1 | |
| SCHEMBL7968303 | 0.71 | SCN9A (0.36) | NFE2L2GPBAR1ALDH1A1 | |
| SCHEMBL7971895 | 0.69 | CYP3A4 (0.36) | L3MBTL1GPBAR1PDCD1LG2CD274 | |
| SCHEMBL7971714 | 0.69 | CA1 (0.36) | L3MBTL1 | |
| SCHEMBL7971991 | 0.67 | KMO (0.38) | GPBAR1 | |
| SCHEMBL2810314 | 0.66 | DYRK1A (0.50) | CLK1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2677978 | 0.65 | CYP1A2 (0.44) | CYP1A1CYP1A2CYP1B1ALDH1A1MAPT | |
| SCHEMBL27792666 | 0.64 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1NFE2L2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |