Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027321 | 0.72 | BACE1 (0.39) | BACE1 | |
| SCHEMBL7956141 | 0.64 | HSD11B1 (0.37) | — | |
| SCHEMBL7967072 | 0.63 | — | — | |
| SCHEMBL6026240 | 0.60 | MCL1 (0.35) | — | |
| SCHEMBL6027361 | 0.58 | HCAR2 (0.38) | EGFRBACE1 | |
| SCHEMBL6026701 | 0.54 | EDNRA (0.43) | — | |
| SCHEMBL782477 | 0.53 | NPY5R (0.31) | — | |
| SCHEMBL23699811 | 0.52 | BACE1 (0.43) | BACE1 | |
| SCHEMBL6026415 | 0.51 | KDM4E (0.47) | BACE1 | |
| SCHEMBL28876333 | 0.50 | NR4A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |