Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.52 |
| ▸ | ITGAV | P06756 | 16/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405357 | 0.91 | ITGAV (0.49) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7405983 | 0.88 | ITGB3 (0.52) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7980567 | 0.88 | ITGB3 (0.51) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7405451 | 0.88 | ITGB3 (0.52) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7985993 | 0.85 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL7986014 | 0.85 | ITGB3 (0.67) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7982182 | 0.85 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL7403109 | 0.85 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7405981 | 0.82 | ITGB3 (0.74) | ITGB3ITGAVITGA2B | |
| SCHEMBL7407086 | 0.80 | ITGB3 (0.46) | ITGB3ITGAVITGB1ITGA5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |