Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.43 |
| ▸ | ITGAV | P06756 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982173 | 0.91 | ITGB3 (0.41) | ITGB3ITGA2BITGAVSMN1; SMN2 | |
| SCHEMBL7982169 | 0.90 | ITGB3 (0.41) | ITGB3ITGA2BITGAVSMN1; SMN2 | |
| SCHEMBL7969254 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL7969337 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BITGAV | |
| SCHEMBL7346960 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BITGAV | |
| SCHEMBL7979200 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BITGAVSMN1; SMN2 | |
| SCHEMBL7982241 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| SCHEMBL7969225 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BITGAVSMN1; SMN2 | |
| SCHEMBL7980538 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL7969293 | 0.78 | ITGB3 (0.43) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |