Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030912 | 0.88 | EDNRA (0.55) | NPC1RAB9ASMN1; SMN2POLBCA12 | |
| SCHEMBL315581 | 0.86 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2POLBCA12 | |
| SCHEMBL315607 | 0.82 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2POLBCA12 | |
| SCHEMBL315528 | 0.82 | MMP2 (0.65) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL4440732 | 0.81 | KDM4E (0.57) | NPC1RAB9ASMN1; SMN2POLBCA12 | |
| SCHEMBL14098011 | 0.81 | MCL1 (0.50) | NPC1RAB9ASMN1; SMN2POLBIDO1 | |
| SCHEMBL14098032 | 0.81 | AKR1C3 (0.43) | NPC1RAB9ASMN1; SMN2POLBIDO1 | |
| SCHEMBL14098037 | 0.81 | AKR1C3 (0.46) | RAB9ASMN1; SMN2POLBIDO1KDM4E | |
| SCHEMBL10383786 | 0.80 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2POLBCA12 | |
| SCHEMBL232284 | 0.79 | HTT (0.50) | NPC1RAB9ASMN1; SMN2POLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207837-B1 | REACTING HALOGEN-SUBSTITUTED PHENYL DERIVATIVE WITH A DISULFIDE COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-03-27 | — | — | US | claimed |
| EP-1026153-A1 | NOVEL PROCESS FOR PRODUCING DIBENZO[b,f]THIEPINE DERIVATIVES | Nippon Suisan Kaisha, Ltd. (JP) | 2000-08-09 | — | — | EP | claimed |
| US-6207837-B1 | REACTING HALOGEN-SUBSTITUTED PHENYL DERIVATIVE WITH A DISULFIDE COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-1026153-A1 | NOVEL PROCESS FOR PRODUCING DIBENZO[b,f]THIEPINE DERIVATIVES | Nippon Suisan Kaisha, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |