Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 12/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983065 | 0.84 | LCK (0.52) | LCK | |
| SCHEMBL7979958 | 0.83 | LCK (0.56) | LCK | |
| SCHEMBL7984553 | 0.81 | FGFR1 (0.49) | FGFR1LCK | |
| SCHEMBL7983561 | 0.81 | LCK (0.47) | LCK | |
| SCHEMBL7970478 | 0.80 | LCK (0.41) | LCK | |
| SCHEMBL7983651 | 0.79 | LCK (0.59) | FGFR1LCKADORA2AADORA1 | |
| SCHEMBL7969694 | 0.78 | LCK (0.38) | LCKADORA2AADORA1CDK9 | |
| SCHEMBL7984051 | 0.78 | LCK (0.45) | LCK | |
| SCHEMBL7983212 | 0.78 | LCK (0.60) | FGFR1LCK | |
| SCHEMBL7983005 | 0.77 | LCK (0.50) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | claimed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |