Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973175 | 1.00 | TSHR (0.51) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7959764 | 1.00 | TSHR (0.51) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7960174 | 1.00 | TSHR (0.51) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7959766 | 1.00 | TSHR (0.51) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7969866 | 1.00 | TSHR (0.51) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL2774395 | 0.96 | TSHR (0.52) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7971333 | 0.96 | TSHR (0.52) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL2770246 | 0.96 | TSHR (0.52) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7969980 | 0.96 | TSHR (0.52) | TSHRKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7973573 | 0.96 | TSHR (0.52) | TSHRKDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |